Test Details: Haptoglobin is an acute-phase protein that is crucial for the elimination of free haemoglobin and the neutralization of oxidative damage. It is produced by the liver. Together, the two proteins are known as the haptoglobin-hemoglobin complex. When red blood cells are damaged, they release more haemoglobin into the bloodstream. That means more of the haptoglobin-hemoglobin complex will be cleared from the body. The Haptoglobin may leave the body faster than the liver can make it. This causes your Haptoglobin blood levels to drop. If your Haptoglobin levels are too low, it may be a sign of a disorder of the red blood cells, such as haemolytic Anemia.