F0079
t(4q12): by FISH PDGFR Alpha Rearrangement (HES) Blood
Test Details: The myeloid/lymphoid neoplasms with eosinophilia and rearrangements of PDGFRA represent a significantly diverse group of hematologic malignancies. Despite the disparate clinical presentations, which include chronic myeloid neoplasms (chronic myelomonocytic leukaemia, chronic myeloproliferative neoplasms, chronic eosinophilic leukaemia) versus more acute myeloid and lymphoid neoplasms (acute myeloid leukaemia, B- and T-lymphoblastic leukaemia/lymphoma and mixed phenotypic acute leukaemias), this diagnostic subgroup shares rearrangements involving 4 specific gene regions: PDGFRA, PDGFRB, FGFR1 and JAK2.
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Category
Cytogenetics
Pre-test Information
Clinical history, CBC Report and treatment status of the patient is required
Report Delivery
10 working days
Gender
All
Organ
Blood, Bone Marrow
t(4q12): by FISH PDGFR Alpha Rearrangement (HES) Blood
6100
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