C0141
C-MYC Gene Rearrangement (Burkitt Lymphoma)
Test Details: C-MYC rearranged B cell lymphomas with a simple karyotype such as that usually seen in Burkitt lymphoma respond better to chemotherapy, while those with a complex karyotype, as is typically seen in Double Hit Lymphomas (DHLs), show a very poor clinical course and are refractory to conventional chemotherapy and even hematopoietic stem cell transplant. FISH studies are useful adjuncts to complete chromosomal studies. A dual-color break-apart c-MYC probe set can detect most c-MYC breaks, but cannot identify the partner gene(s).
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Category
Cytogenetics
Pre-test Information
H & E report, grossing details, duration of fixation, clinical details and site of lesion / biopsy is required.
Report Delivery
4 working days
Gender
All
Organ
Blood / Bone marrow / FFPE
C-MYC Gene Rearrangement (Burkitt Lymphoma)
3750
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