Test Details: Neuron-specific enolase (NSE) is an enzyme that is found in the cytoplasm of neurons and neuroendocrine cells. The test is conducted to detect neuroendocrine tumours specially those associated with small cell lung carcinoma. This test detects the neuron specific enolase (NSE) in serum to follow up marker in patients with neuron specific enolase secreting tumours of any type.