I0149
IHC- Thyroid transcription factor 1 (TTF1)
Test Details: Immunohistochemical testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody. Thyroid transcription factor (TTF-1 also known as NKX2-1 or thyroid-specific enhancer-binding protein) is widely used as a specific and sensitive marker for the majority of bronchopulmonary adenocarcinomas and pulmonary small cell carcinoma in addition to follicular, papillary, and medullary thyroid carcinomas. A lesser degree of expression is found in large cell carcinoma of the lung, undifferentiated thyroid carcinoma, non-pulmonary small cell carcinoma of different locations, subset of extrahepatic cholangiocarcinomas, glial-ependymal and choroid plexus tumours, pituicytoma, granular cell tumour of the sellar region, meningeal tumours.
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Category
Advanced Routine Diagnostics
Pre-test Information
Demographic data, site of the specimen, clinical details & relevant investigations including radiology are mandatory.
Report Delivery
4 days after releasing H&E report
Gender
All
Organ
Multi-Organ
IHC- Thyroid transcription factor 1 (TTF1)
1570
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