Test Details: A D-dimer test is a blood test that measures D-dimer, which is a protein fragment, the body makes when a blood clot dissolves in the body. This test is utilized to detect multiple blood clotting disorders. These disorders include: Deep vein thrombosis (DVT), Pulmonary Embolism, Disseminated Intravascular Coagulation (DIC). Other conditions that can cause high D-dimer levels include pregnancy, heart disease, and recent surgery.