Test Details: Alpha-2-macroglobulin is a protease inhibitor and is one of the largest plasma proteins. It transports hormones and enzymes, exhibits effector and inhibitor functions in the development of the lymphatic system, and inhibits components of the complement system and haemostasis system. Increased concentrations are associated with patients with some Chronic liver diseases, Nephrotic syndrome, and Diabetes. Decreased concentrations are associated in patients with Pancreatitis, Rheumatoid arthritis and Multiple myeloma.