F0067
FISH for MDS [All markers (8)]
Number of Tests | 8 |
Test Included | del 5q, del 7q, del 20q, cMYC amplifications / Trisomy 8, inv 3, MLL amplification, 17p del, 13q del |
Test Details: Myelodysplastic syndromes (MDSs) are heterogeneous hematopoietic disorders associated with various degrees of myelosuppression and transformation into acute leukaemia. Complete loss of chromosome 7 (monosomy 7) or partial deletion involving its long arm [del(7q)] are highly recurrent chromosomal aberrations in myeloid disorders, including myelodysplastic syndrome (MDS).inv(3)(q21q26.2)/t(3;3)(q21;q26.2) is a distinct clinicopathologic entity with a poor prognosis. Deletion of 13q, 17p have a known prognostic value and play an important role in pathogenesis and evolution, determining patient's outcome and therapeutic strategies. Fluorescence in situ hybridization (FISH) complements conventional karyotyping by the ability to evaluate large numbers of both interphase and metaphase nuclei. This has an important diagnostic and prognostic role which affects the choice of therapies.
![](assets/img/diagnleftimg.png)
Category
Cytogenetics
Pre-test Information
Clinical history, CBC report and treatment status of the patient is mandatory.
Report Delivery
4 working days
Gender
All
Organ
Blood / Bone Marrow
FISH for MDS [All markers (8)]
11500
Most Searched Diagnostic Tests