H0098
High Resolution HLA Typing - A, B, C, DR, DQ
Number of Tests | 5 |
Test Included | HLA A, HLA B, HLA C, HLA DR, HLA DQ |
Test Details: Human Leukocyte Antigen (HLA) typing is of clinical significance in determining tissue compatibility or HLA matching between donor and recipient transplant patients and also in the assessment of disease associations. Matching the HLA loci is essential for successful transplantation. The International ImMunoGeneTics information system (IMGT)/HLA database is used as reference for HLA A, B, C, DR and DQ typing. HLA A, B, C, DR and DQ typing shows 100% specificity and 100% sensitivity. In sequencing, full gene is covered for Class I (A, B and C). For Class II (DRB1 and DQB1) exons 2-4 are covered including the intronic regions in between.
Accurate HLA matching between donor and patient significantly improves overall transplant survival, reduces the incidence and severity of both acute and chronic graft versus host disease (GVHD) thereby, improving the rate of engraftment. This has utmost importance in haematopoietic marrow transplants.
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Category
Histocompatibility
Pre-test Information
Sample is to be collected only after 3 days of last dialysis or after three weeks of last blood transfusion. Duly filled HLA TRF along with normal TRF, Photo Id and photo of patient are mandatory.
Report Delivery
16 working days
Gender
All
Organ
Multi-Organ
High Resolution HLA Typing - A, B, C, DR, DQ
12000
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