Test Details: Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombosis and/or specific pregnancy-related death. Based on various studies and classification criteria, the laboratory requirements for diagnosing APS include the presence of at least one of the following: lupus anticoagulant, anticardiolipin and anti-beta2 glycoprotein IgG or IgM antibodies. Indication for this test are inappropriate blood clotting, frequent miscarriages, stroke and heart attack.