Test Details: Immunohistochemical testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody. In routine immunohistochemistry, the expression of TLE-1 is mostly characteristic for synovial sarcoma; however, the overexpression of TLE-1 is also reported in different soft tissue tumours including endometrial stromal sarcoma, acral myxoinflammatory fibroblastic sarcoma, solitary fibrous tumour, epithelioid sarcoma, lipoma and liposarcoma, leiomyosarcoma, neurofibroma, malignant nerve sheath tumour, chordoma, mesothelioma, and undifferentiated pleomorphic sarcoma.