I0111
IHC-MSH2
Test Details: Immunohistochemical testing helps to identify specific antigens (proteins) within tissue sections utilizing an antigen-specific antibody. MutS Homologue 2 (MSH2) is a Mismatch repair (MMR) protein. Its deficiency results in microsatellite instability (MSI). Defective MMR will show loss of expression of the protein. Loss of nuclear expression of MSH2 indicates high probability of Lynch syndrome (sequencing and/or large deletion/duplication testing of germline MSH2 may be indicated).
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Category
Advanced Routine Diagnostics
Pre-test Information
Demographic data, site of the specimen, clinical details & relevant investigations including radiology are mandatory.
Report Delivery
4 days after releasing H&E report
Gender
All
Organ
Multi-Organ
IHC-MSH2
1570
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